Episode 003 — PMS, Histamine & Hormones: What’s Really Going On?
There’s a viral trend going around — women taking Zyrtec, Claritin, and Pepcid before their periods and reporting that their PMS and PMDD symptoms are dramatically better. And honestly? It’s working. But why?
In this episode, I break down the real reason antihistamines are helping — and what it’s actually telling you about what’s going on inside your body. Because the trend is onto something. It’s just not the whole story.
We cover:
How estrogen and progesterone directly control histamine release — and what happens when they fall out of balance
Why histamine isn’t just an allergy problem — and how it drives mood swings, anxiety, bloating, and migraines
The feedback loop that keeps symptoms stuck and makes them worse over time
Two key genetic variants that explain why you might struggle more than your sister, your friend, or the woman next to you
What a root cause approach actually looks like — and where antihistamines fit in
Whether you’re in your 30s dealing with PMDD or in your 40s wondering why perimenopause is hitting differently than you expected — this episode will give you a framework for understanding what’s really going on, and what’s worth addressing first.
